A love letter to my glovebox

Dear Glovebox,

I’ve only had you for a few months now, but I think it’s time I go public with the way I’m feeling. I love working with you.

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Now, I know some people say that you’re “over-the-top,” but that’s what I love about you. Sure, not everyone has a glovebox, so I will eventually have to demonstrate reactions on the Schlenck line. That said, setting up a screen with air sensitive reagents and NOT having to deal with N2 balloons, umbrellas, or other methods of keeping things safe is the greatest thing. I can’t remember what it’s like to use BuLi as a solution anymore; weighing it out as a solid is the single easiest thing I can think of!

So, this is my way of thanking you, glovebox, for making my life that much easier and for allowing me to discover chemistry I wouldn’t otherwise be able to observe without a pristine atmosphere. You let me revel in my OCD concerning reagent purity, and that’s never a bad thing!

For those who don’t understand my love, see this macrocrystalline sample of LiHMDS:

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Pretty, right? I’m not sure I could ever have conceived of isolating this outside of the glovebox!

Yours truly,

Organometallica

Below the cut, some more pictures of pretty things from the box that I have lying about. Most often, I take pictures because my advisor is constantly asking what color my products are. :face palm:

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RIP Prof Daniel Havey

In a rare and unfortunate double post on CBC, I’d like to extend my condolences to the family and friends of Prof. Daniel Havey, a JMU professor of chemistry. While I didn’t know him, I know for a fact that his passing is a great loss for his students, former and current.

The official JMU statement: http://bit.ly/Wcb8Zs 

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Daniel Havey, photo 2009, courtesy of JMU

Blog Syn nabs the limelight

Blog Syn nabs the limelight

So for those who didn’t know, I’ve recently contributed to the new grassroots chemistry sensation, Blog Syn. More importantly, several news outlets have written about it (though no one’s yet asked me for a comment, despite getting the best yield. ;) Wonk wonk). Featured here is Nature’s coverage. Stay tuned to Blog Syn for some more exciting articles forthcoming!

Mental Health in Graduate School

If you’ve been following the chemistry blogosphere, you know that Chemjobber and Vinylogous have been having a conversation of sorts regarding mental health in graduate school, and I figured I would give my input.

To give some background, I am a second year graduate student at a top five program in organic chemistry, and up until ~ 6 months ago, I was miserable. However, I think it honestly had little to do with graduate school itself, and more my working relationship with my advisor; I found out the hard way, like many on the participating blogs have pointed out, that a horrible advisor can account for the greatest source of stress in graduate school. I changed advisors, and I was tempted to write about it at the time, but decided not to for a variety of reasons.

Given that I don’t have the benefit of anonymity, I won’t discuss the terms of why I left my previous lab. However, I will say that I was under a lot of pressure to produce results, and the manner in which the lab was run isolated students in terms of how obvious it was around the lab that someone was taking a beating. As a result, the weeks where I would work all seven days, only sleeping at my desk for a few hours, it was very easy to feel cut off from the world, even within the chemistry department. The person I shared a bay with was a seventh year graduate student fighting to get out in one piece, and with student-advisor conflicts arising constantly, I very nearly dropped out of graduate school altogether. I remember going home to visit family one holiday and nearly having a nervous breakdown describing my work schedule, and that feeling just built over time. By the time I had spent a year in the lab, I was reclusive, paranoid, quiet, and downright depressed.

However, my story has a happy ending. As I was thinking very seriously about calling my boss from a company I used to work for and beg for my old job back, I happened to meet a new assistant professor in the department, who told me about her research. I was interested enough that I made the decision to stay and switch advisors; once you drop out, you’re done, but if I could make it work in another lab, maybe I could at least get a degree out of this mess.

The biggest barrier to actually changing labs was somehow convincing myself that I wasn’t a bad person for doing so. For some reason, I had it in my head that I would be seen as a failure or a weakling if I changed groups. “He couldn’t cut it in Prof. X’s group,” they would surely say. “He’s so pathetic,” they might add. I can’t say for sure whether that was or wasn’t said, but I swallowed my fears and realized that if I was going to be sane and healthy, I couldn’t give a crap about what other people said. I remember discussing the possibility of working with Alison on a Tuesday (at that point I hadn’t realized that she had only started at the University two weeks before, and so I can’t imagine in retrospect how crazy it must have been from her perspective), and by Friday night I was in her lab, setting up reactions.

I make it seem somewhat straightforward, and I admit that making a change sooner than later likely helped the situation along, but it was terrifying. For weeks I was worried if I had made a mistake, if, had I stayed in my previous lab, I would have persevered and seen a happier me on the other side. It was a surprisingly stressful time, largely because no one really tells you how changing groups will go. You hear stories of people who have done it, and you know that it’s possible, but it’s not something that many people encourage. However, if you’re having problems with your advisor, know that history repeats itself. Be proactive about yourself and your career. Regardless of the outcome, at least you will have exerted some control over your situation. For me, it was like night and day. Alison and I work together phenomenally well; we share many fundamental ideas of how research should be done, she respects the skills that I have, and she’s also not afraid to teach me to do things better. More than anything, though, being on the same page has made it much easier to understand what’s expected of me, and know where I stand. I still work just as hard, but now it’s because I want to, not because I’m being pressured by an advisor. To wit, we’re already putting the pieces of our first manuscript together, six months in, something I was worried I would never get to in my previous lab.

More importantly, though, the above changes in perception to how I operated in the lab made me feel more relaxed and outgoing than I ever was previously, despite still working “crazy” hours. Shortly after changing labs I began seeing my current girlfriend, I started some hobbies (as you may or may not know, I am a budding amateur aquarist now!), and overall I respond to “how are you doing” with “pretty well” instead of “I’m not dead yet.”

I suppose this was an ad hoc story that summarizes to the point that grad school is incredibly difficult, but it doesn’t need to be demoralizing. I think too many people (especially organic chemists) assume that being beaten down by their advisor is “part of the process,” but I think I’ve proved that this is hardly true. By taking control of the situation and identifying what was bothering me (my choice of advisor) and changing the heart of the problem, I’m happier and more productive than I ever would have imagined I could be in graduate school. That said, I’m still poor and tired, but at least I’m still living the #phdlife.

How to draw catalytic cycles in ChemDraw

So it’s NSF proposal and seminar season at UIUC and all of the ugliest catalytic cycles are on display around the department. No, I’m not talking about the reactions themselves, but those circular arrows. Ugh! Gross!

If your cycles look like the one on the right, FOR SHAME.

I realized that this is not something they teach in class, so as a public service, I created this video on how one can make gorgeous catalytic cycles using ChemDraw’s Pen Tool.

You’re welcome.

Ernst Otto Fischer: 2012-2012

Some boys have dogs to keep them company. Others have housecats to curl up and make them feel alright. When I joined the Fout lab as the only graduate student, I’ll admit that it was lonely. Being alone in lab has its perks, but sometimes you just wish you had someone to talk to. For me, I (quite unexpectedly) found that companionship in a tiny Betta fish named Ernst (Ernie, colloquially). Originally just a whim, something to put in an old 3L flask with an oddly-sized neck, I grew to love Ernie. He had a lot of energy for a fish, and always swam up to greet me when I came into the office (sure, he just wanted food, but I pretended he wanted my company). It wasn’t another person, but I was surprised by how good a surrogate caring for a fish could be.

Yesterday I noticed Ernie swimming a little oddly, and realized that his color was a bit off (as a colorblind person, I don’t always pick up on those changes right away). Immediately, I went to the fish blogosphere and realized he probably had velvet, or at least some form of aquatic parasite. I ordered some fish medicine, which arrived this morning. I went to the mailroom to pick it up, but before I could get the medicine into his bowl, it was too late.

Here’s to my fishy friend, Ernst Otto Fischer, who was graced with a burial at sea this morning at 11am. May you find many bloodworms wherever you are now.

Complex Conjugate

Complex Conjugate

So I went ahead and made my love of chemistry both public and permanent. I’m hoping to get a matching psi on my right arm to complete the Schrodinger equation, but that’s for another time.

Dearest readers, please share your science tattoos here! I would love to see some that you’ve had done!